Monte Carlo Simulation-Guided Design for Size-Tuned Tumor Spheroid Formation in 3D Printed Microwells

    April 2024 in “ Biotechnology Progress
    İsmail Eş, Ana‐Maria Theodora Ionescu, Burak M. Görmüş … Lucimara Gaziola de la Torre
    Studysummary This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.
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    Research cited in this study 1

    1. Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration ACS Applied Materials & Interfaces · 2016