Search

everythinglearnresearchcommunity

for

Search:↓

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Androgens can help prevent memory problems caused by apoE4.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Early hormones shape sex-specific differences in rat glands.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Muscles can make their own androgens, which may help muscle growth.

Dosing time affects finasteride's effectiveness and safety in rats.

New protein changes may be involved in the immune attack on hair follicles in alopecia areata.

Keratins are important for skin cell health and their problems can cause diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Certain nutrients can help keep skin healthy as we age.

Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Low-dose oral Minoxidil is an effective treatment for hair loss with minimal serious side effects.

pH changes are crucial for root hair growth because they affect enzymes and proteins that control the cell wall and growth.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Different enzymes are active in different parts of developing mouse organs.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.