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    Glossary MHC class I

    present protein fragments to cytotoxic T cells for immune response

    MHC class I, or Major Histocompatibility Complex class I, are molecules found on the surface of almost all nucleated cells in the body. They play a crucial role in the immune system by presenting small fragments of proteins (peptides) from inside the cell to cytotoxic T cells. This helps the immune system recognize and destroy infected or cancerous cells.

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    1. MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression The Journal of Immunology · 2006 · 16 citations
    2. T-cell “induced-self” MHC class I/peptide complexes may enable “de novo” tolerance induction to neo-antigens occurring outside of the thymus Experimental dermatology · 2016 · 8 citations
    3. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations
    4. Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A*33:01 ; B*14:02; C*08:02 as a genetic marker Australasian Journal of Dermatology · 2019 · 7 citations
    5. Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata Journal of Investigative Dermatology · 2005 · 44 citations
    6. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007 · 253 citations
    7. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    8. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    9. Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege Journal of Investigative Dermatology · 2005 · 139 citations
    10. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia (Alopecia Areata) in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008 · 69 citations
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