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    Glossary MICA

    protein involved in immune response and stress detection

    MICA stands for MHC class I polypeptide-related sequence A. It is a protein that is part of the immune system and is involved in the body's response to stress and infection. MICA is expressed on the surface of certain cells and can be recognized by natural killer (NK) cells, which play a role in targeting and destroying infected or cancerous cells. In the context of hair and alopecia, variations in the MICA gene have been studied for their potential association with autoimmune conditions like alopecia areata.

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    1. Mica

    Research 10 of 762

    1. Joint study of the associations of HLA‐B and the transmembrane short tandem repeat polymorphism of MICA protein with alopecia areata shows independent associations of both with the disease Clinical and Experimental Dermatology · 2020 · 7 citations
    2. Alopecia Areata is associated with MICA and an extended HLA haplotype Journal of the American Academy of Dermatology · 2004 · 1 citations
    3. 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    4. 026 Targeting pathogenic MICA-NKG2D interactions by statins: A novel adjunct treatment strategy for alopecia areata management? Journal of Investigative Dermatology · 2022
    5. ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    6. Alopecia areata: a review of disease pathogenesis 2018 · 191 citations
    7. Alopecia areata: Animal models illuminate autoimmune pathogenesis and novel immunotherapeutic strategies Autoimmunity reviews · 2016 · 82 citations
    8. The PDE4 inhibitor, apremilast, suppresses experimentally induced alopecia areata in human skin in vivo Journal of Dermatological Science · 2014 · 52 citations
    9. Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata Journal of Investigative Dermatology · 2005 · 44 citations
    10. Alopecia Areata: A Review of the Role of Oxidative Stress, Possible Biomarkers, and Potential Novel Therapeutic Approaches Antioxidants · 2023 · 15 citations
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