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GlossaryMHC Class II

molecules on immune cells presenting antigens to T-helper cells

MHC Class II, or Major Histocompatibility Complex Class II, are molecules found on the surface of certain immune cells, such as dendritic cells, macrophages, and B cells. They play a crucial role in the immune system by presenting foreign antigens to T-helper cells, which then activate other immune responses to fight off infections.

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Possible Role of ILC1 in the Pathogenesis of Alopecia Areata

research Possible Role of ILC1 in the Pathogenesis of Alopecia Areata

3 citations , April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

ILC1 cells contribute to hair loss in alopecia areata.

Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege

research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege

47 citations , December 2011 in “Experimental Dermatology”

CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.

research Innate Lymphoid Cells Type 1 May Be New, Non-Antigen-Specific Player in the Pathogenesis of Alopecia Areata

September 2019 in “Journal of Investigative Dermatology”

Innate lymphoid cells type 1 may contribute to alopecia areata.

Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata

research Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata

April 2023 in “Journal of Investigative Dermatology”

The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.

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