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    Glossary MHC Class II

    molecules on immune cells presenting antigens to T-helper cells

    MHC Class II, or Major Histocompatibility Complex Class II, are molecules found on the surface of certain immune cells, such as dendritic cells, macrophages, and B cells. They play a crucial role in the immune system by presenting foreign antigens to T-helper cells, which then activate other immune responses to fight off infections.

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    1. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    2. Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia (Alopecia Areata) in a C3H/HeJ Mouse Model ˜The œAmerican journal of pathology · 2008 · 69 citations
    3. Calcitonin gene‐related peptide (CGRP) may award relative protection from interferon‐γ‐induced collapse of human hair follicle immune privilege Experimental Dermatology · 2011 · 47 citations
    4. Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia? Clinical and Experimental Dermatology · 2009 · 39 citations
    5. Can the Hair Follicle Become a Model for Studying Selected Aspects of Human Ocular Immune Privilege? Investigative Ophthalmology & Visual Science · 2011 · 21 citations
    6. Self Prion Protein Peptides are Immunogenic in Lewis Rats Journal of autoimmunity · 2001 · 14 citations
    7. UVB-induced depletion of donor-derived dendritic cells prevents allograft rejection of immune-privileged hair follicles in humanized mice American journal of transplantation · 2018 · 6 citations
    8. Pathophysiology of Alopecia Areata in the Pediatric Patient Pediatric Dermatology · 2025 · 5 citations
    9. The Function and Structure of the Skin 2014 · 4 citations
    10. 516 Possible role of ILC1 in the pathogenesis of alopecia areata (AA) 2019 · 3 citations
    11. Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata Frontiers in Medicine · 2026
    12. Image 1_Resident T cell activation leads to human hair follicle immune privilege loss ex vivo, which is prevented by the DHODH inhibitor farudodstat: relevance for alopecia areata.pdf Figshare · 2026
    13. MẤT CÂN BẰNG GIỮA TẾ BÀO T ĐIỀU HÒA VÀ TẾ BÀO T GÂY ĐỘC TẾ BÀO TRONG RỤNG TÓC TỪNG MẢNG: KHI ĐẶC QUYỀN MIỄN DỊCH SỤP ĐỔ Tạp chí Da liễu học Việt Nam · 2026
    14. Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege International Journal of Cosmetic Science · 2024
    15. 1419 Pre-clinical in-vitro assays for high throughput screening of drug candidates for protection and restoration of immune privilege in alopecia areata Journal of Investigative Dermatology · 2023
    16. 865 Single-cell protein activity inference analysis of full-thickness skin uncovers novel pathways and a rare Arg1+ macrophage population in AA Journal of Investigative Dermatology · 2022
    17. 022 Exploring the potential of the novel IFNγ aptamer TAGX-0003 as a treatment for alopeciaareata in pre-clinical models 2021
    18. 431 Innate lymphoid cells type 1 may be new, non-antigen-specific player in the pathogenesis of alopecia areata Journal of Investigative Dermatology · 2019
    19. 584 Dandruff is associated with perturbations of hair follicle immune privilege, and the infundibular and epidermal immune microenvironment Journal of Investigative Dermatology · 2022
    20. 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo 2018
    21. Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata Journal of Investigative Dermatology · 2007 · 36 citations
    22. MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression The Journal of Immunology · 2006 · 16 citations
    23. Alopecia areata update Journal of The American Academy of Dermatology · 2010 · 391 citations
    24. Alopecia areata update Journal of The American Academy of Dermatology · 2000 · 49 citations
    25. Skin Commensal Antigens: Taking the Road Less Traveled Trends in Immunology · 2018
    26. Alopecia Areata KARGER eBooks · 2008 · 24 citations
    27. Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia Experimental Dermatology · 2005 · 7 citations
    28. Probing the Effects of Stress Mediators on the Human Hair Follicle American Journal of Pathology · 2007 · 159 citations
    29. Major Histocompatibility Complex Class I Chain-Related Gene A Polymorphisms and Extended Haplotypes Are Associated with Familial Alopecia Areata Journal of Investigative Dermatology · 2005 · 44 citations
    30. Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege Journal of Investigative Dermatology · 2005 · 139 citations