Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata
April 2023
in “
Journal of Investigative Dermatology
”
Studysummary This research developed new in vitro models for high-throughput screening of drugs that could protect or restore immune privilege in hair follicles, finding that Tofacitinib was effective in preventing inflammation-related marker upregulation, while Tacrolimus and αMSH worked specifically in outer root sheath keratinocytes.
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