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GlossaryKeratinocytes (NHEK)

cells in the epidermis that produce protective keratin protein

Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. These cells produce keratin, a protein that helps protect the skin from environmental damage, pathogens, and water loss. They play a crucial role in the skin's barrier function and are involved in wound healing and the formation of hair and nails.

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Cystine-Thiamin-Containing Hair-Growth Formulation Modulates the Response to UV Radiation in an In Vitro Model for Growth-Limiting Conditions of Human Keratinocytes

research Cystine-Thiamin-Containing Hair-Growth Formulation Modulates the Response to UV Radiation in an In Vitro Model for Growth-Limiting Conditions of Human Keratinocytes

9 citations, September 2018 in “Journal of Photochemistry and Photobiology B-biology”

A hair-growth formula with cystine and thiamin helps protect skin cells against UV damage and improves their growth.

Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata

research Pre-Clinical In-Vitro Assays for High Throughput Screening of Drug Candidates for Protection and Restoration of Immune Privilege in Alopecia Areata

April 2023 in “Journal of Investigative Dermatology”

The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.

research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis

April 2023 in “Journal of Investigative Dermatology”

Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.

Generation of Human Hair Follicle Organoids In Vitro and Ex Vivo by Co-Culture of Primary Human Hair Matrix Keratinocytes and Dermal Papilla Fibroblasts

research Generation of Human Hair Follicle Organoids In Vitro and Ex Vivo by Co-Culture of Primary Human Hair Matrix Keratinocytes and Dermal Papilla Fibroblasts

June 2020 in “Journal of Investigative Dermatology”

Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.

research SIG-1451: A Topical Anti-Inflammatory New Chemical Entity for Atopic Dermatitis

April 2017 in “Journal of Investigative Dermatology”

SIG-1451 could be a promising new treatment for atopic dermatitis.

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