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This review highlights the role of keratin mutations in epidermolysis bullosa simplex and the resulting chronic inflammation, but it presents no new experimental findings.

This review summarizes recent findings on keratins 6, 16, and 17, highlighting their role in keratinocyte behavior and nuclear functions, and discusses their potential as biomarkers for various skin pathologies, including damage, inflammation, and cancer, rather than in healthy skin.

This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.

This study reviews the etiology and treatment of skin cancer, focusing on nanotechnology's role in addressing drug resistance and evaluating nanoparticles' potential to improve treatment outcomes, including overcoming multidrug resistance.

This review discusses the role of YAP/TAZ proteins in skin cancer physiology and tumorigenesis, and the potential of targeting these proteins in skin cancer treatments, but presents no new experimental findings.

This review highlights recent advances in the design of nanocarrier systems for transdermal drug delivery, detailing their potential to improve treatment precision for dermatologic conditions despite challenges like formulation stability and scalability.

This review article highlights the potential of mesenchymal stem cells, their exosomes, and non-coding RNAs in repairing aging skin tissues due to their ability to secrete beneficial compounds, suggesting their promising role in photoaging treatment without causing immune rejection or granuloma formation.

Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.

This review summarizes current evidence on how beta-human papillomavirus and Merkel cell polyomavirus may contribute to the development of nonmelanoma and Merkel cell skin carcinomas, respectively, but it reports no new clinical findings.

This review explores the role of Tregs in autoimmune skin diseases, transplantation, and skin cancer, and discusses Tregs-based therapies' potential for treating autoimmunity without reporting new experimental results.

This study suggests that biallelic loss of the Hedgehog signaling repressor Patched alone in Keratin 5+ epidermal cells is insufficient to drive basal cell carcinoma development unless exogenous stimuli trigger accumulation of BCC precursor cells.

This narrative review explores the strong association between various chronic inflammatory skin diseases and metabolic syndrome, emphasizing shared inflammatory pathways and chemokine involvement, though the precise molecular connections remain partially understood.

This review reports that transcriptional and epigenetic mechanisms in epithelial stem cells guide their fate in the epidermis and hair follicles, crucial for skin homeostasis, but disruptions can lead to disease.

This paper reviews advancements in 3D human skin models using bioprinting, organoid, and organ-on-a-chip technologies, noting improvements in physiological realism through vascularization and multi-omics data, but also highlighting challenges such as cost and lack of standardization that hinder clinical adoption.

In this study, researchers presented cases of cellular neurothekeoma in three male family members with early-onset in infancy, suggesting a potential genetic component and inheritance pattern, which deviates from the typical presentation seen mostly in women between 20–30 years.

In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.

In this review, the authors discuss how hair may protect against scalp skin cancer by enabling IL-17-biased immunosurveillance, while hair loss could permit tumor development by reducing this immune protection.

This review by two dermatologists suggests that hair on the human scalp may protect against skin cancer not just physically, but by enabling IL-17 immune surveillance, with hair loss potentially leading to increased tumor growth due to reduced immunosurveillance.

In this review, the authors propose that hair on the scalp may protect against non-melanoma skin cancer by maintaining an IL-17 biased immunosurveillance, with hair loss potentially increasing the risk of skin cancer due to disrupted immune monitoring.

ITK inhibitors may effectively treat alopecia areata.

In this case report, a 9-year-old boy with Sjogren-Larsson syndrome was also diagnosed with central precocious puberty, showing genetic mutations and increased hormone levels; he was treated with triptorelin acetate for CPP but experienced growth delay during follow-up.

This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.

This paper is a compilation of chapters discussing various aspects of cosmetic dermatology and surgery but reports no new clinical results.

A young man was unexpectedly diagnosed with basal cell carcinoma after a scalp examination and confocal microscopy.

In this study, Makarova et al. found that topical vitamin D3 significantly delayed basal cell carcinoma development in UVR-exposed, BCC-prone mice, while oral vitamin D3 supplements did not prevent carcinogenesis, suggesting a potential role of UV-induced vitamin D3 in inhibiting tumor growth.

This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.

This study found that the CTLA-4 gene polymorphism (rs733618) has no association with polycystic ovarian syndrome in the studied population.

In this study, women with polycystic ovary syndrome showed higher scores in character strengths like hope and judgement compared to those without PCOS.

This study found that the cosmetic olfactory receptor agonist cyclohexyl salicylate may stimulate hair growth and expand stem cell progeny, suggesting potential as a cosmetic adjuvant for hair loss.

In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.