Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology

    February 2026 in “ International Journal of Molecular Sciences ”
    Lei Li, Wenqi Si, Zhehu Jin, Wenyu Jin
    Studysummary This paper reviews advancements in 3D human skin models using bioprinting, organoid, and organ-on-a-chip technologies, noting improvements in physiological realism through vascularization and multi-omics data, but also highlighting challenges such as cost and lack of standardization that hinder clinical adoption.
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    3. Advancements In 3D Skin Bioprinting: Processes, Bioinks, Applications And Sensor Integration International Journal of Extreme Manufacturing · 2024
    4. A Biopsy-Sized 3D Skin Model With a Perifollicular Vascular Plexus Enables Studying Immune Cell Trafficking in the Skin Biofabrication · 2024
    5. Applications of Human Pluripotent Stem Cell-Derived Skin Organoids in Dermatology ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2023
    6. Emerging 3D Bioprinting Applications in Plastic Surgery Biomaterials Research · 2023