Cystathionine Beta-Synthase-Deficient Mice Thrive on a Low-Methionine Diet

November 2013 in “ The FASEB journal ”

Sapna Gupta, Stepan Melnyk, Warren D. Kruger

Cystathionine β-synthase deficiency methionine-restricted diet homocysteine alopecia Scd-1 expression bone density CBS deficiency MRD tHcy hair loss

Studysummary In this study, a low-methionine diet significantly improved the health and physical traits of cystathionine β-synthase-deficient mice, contrasting with negative effects on mice with partial deficiency.

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