Case Report: Treatment-Resistant Pityriasis Rubra Pilaris Achieving Remission with Ustekinumab
March 2021
in “
Australasian Journal of Dermatology
”
Studysummary This case study reports a 70-year-old man with treatment-resistant pityriasis rubra pilaris achieving complete clinical remission with ustekinumab, adding to evidence supporting biologic therapy when TNF inhibitors are unsuitable.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document from 2021 summarized various dermatological studies and case reports, with a focus on alopecia areata (AA) and its treatment challenges. It highlighted the limited success of corticosteroids and JAK inhibitors for AA due to the disease's unpredictable nature, though a systematic review suggested potential effectiveness of JAK inhibitors, warranting further evidence. The document also covered a range of other dermatological conditions and treatments, including the efficacy of tildrakizumab for psoriatic arthritis, the role of multidisciplinary clinics in managing skin cancers, and the use of AI in diagnosing melanoma. Additionally, it reported on the psychological impact of skin diseases, the need for improved dermatology training, and the potential of photo bio-modulation for treating fibrosing alopecia and nail dystrophy.
