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GlossaryCyclosporine

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment

research A Multicenter Placebo-Controlled Clinical Trial on the Efficacy of Oral Ciclosporin A in the Treatment of Canine Idiopathic Sebaceous Adenitis Compared with Conventional Topical Treatment

24 citations, May 2010 in “Veterinary dermatology”

Oral ciclosporin A and topical treatments both reduce hair loss and scaling in dogs with sebaceous adenitis, but using both together is most effective.

Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

research Exfoliative Cutaneous Lupus Erythematosus in German Shorthaired Pointer Dogs: Disease Development, Progression, and Evaluation of Three Immunomodulatory Drugs (Ciclosporin, Hydroxychloroquine, and Adalimumab) in a Controlled Environment

21 citations, April 2010 in “Veterinary Dermatology”

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

research Successful Treatment of Sebaceous Adenitis in a Rabbit with Ciclosporin and Triglycerides

13 citations, December 2008 in “Veterinary dermatology”

A rabbit with sebaceous adenitis was effectively treated with ciclosporin and medium-chain triglycerides.

research Role of Ciclosporin in Steroid-Responsive Sudden Sensorineural Hearing Loss

8 citations, January 2005 in “Acta Oto-Laryngologica”

Ciclosporin might be a good alternative treatment for certain hearing loss that responds to steroids.

research Simvastatin-Induced Myoglobinuric Acute Kidney Injury Following Ciclosporin Treatment for Alopecia Universalis

3 citations, February 2010 in “Clinical kidney journal”

Combining ciclosporin and simvastatin can cause severe kidney damage.

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community New potential hair loss treatment (news release)

in Treatment 186 upvotes 4 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community how to compound topical cyclosporine

in Treatment 9 upvotes 2 years ago

The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.

community RT1640 - Gray Hair Reversal Recipe

in Research/Science 3 upvotes 2 years ago

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 month ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community Starting Way-316606 for the first time today.

in Research/Science 30 upvotes 3 weeks ago

A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

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