research Lineage Commitment of Dermal Fibroblast Progenitors Is Mediated by Chromatin De-repression
Skin cell types develop when specific genes are turned on by removing certain chemical tags from DNA.
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research Ligand-Independent Actions of Vitamin D Receptor
The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.
research DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells
Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.
research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients
The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
research Chrousos Syndrome: From Molecular Pathogenesis to Therapeutic Management
The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
research PKC Downregulation Upon Rapamycin Treatment Attenuates Mitochondrial Disease
Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
research Wnt1a Maintains Characteristics of Dermal Papilla Cells That Induce Mouse Hair Regeneration in a 3D Preculture System
Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
research Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research Role of Environmental Factors and Gonadotoxin Exposure in Unexplained Male Infertility
Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research Transcriptional Regulation of the Thymus Master Regulator Foxn1
Foxn1 gene regulation is crucial for thymus development but not for hair growth.
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research Oral Contraceptive Pill Treatment Alters Gene Expression of Inflammatory Markers in Polycystic Ovary Syndrome Women
Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
research Hidradenitis Suppurativa: A Folliculotropic Disease of Innate Immune Barrier Dysfunction?
Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.
research The Circular RNA circNlgn Mediates Doxorubicin-Induced Cardiac Remodeling and Fibrosis
A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.
research Lamins in Development, Tissue Maintenance, and Stress
Lamins are vital for cell survival, organ development, and preventing premature aging.
research Apoptosis and Cutaneous Biology
Apoptosis is crucial for healthy skin and treating skin diseases.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Signaling Couples Hair Follicle Stem Cell Quiescence With Reduced Histone H3 K4/K9/K27me3 for Proper Tissue Homeostasis
Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
research Effect of Ultraviolet Radiation, Smoking, and Nutrition on Hair
Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
research Genomewide Differential Expression Profiling of Long Non-Coding RNAs in Androgenetic Alopecia in a Chinese Male Population
Found different long non-coding RNAs in balding Chinese men, which may help create new treatments.
research Abstracts of 42nd National Conference of Association of Clinical Biochemists of India (ACBICON 2015)
The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
research Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
research Estrogens and Aging Skin
Estrogen therapy can reduce skin aging but has cancer risks.
research The Circadian Clock in Skin
The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.
research Oral Retinoids in Dermatology
Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Basics of Androgen Synthesis and Action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.