Expansion Culture of Hair Follicle Stem Cells Through Uniform Aggregation in Microwell Array Devices

The document discusses a new method for expanding hair follicle stem cells (HFSCs) using a microwell array device. The researchers found that HFSCs cultured in this device formed aggregates and expanded more effectively than in a traditional flat culture. The expanded HFSCs maintained their stem cell characteristics, as evidenced by the expression of stem cell markers. The study also demonstrated that these expanded HFSCs could induce hair regeneration when transplanted into mice. Furthermore, the researchers successfully expanded human HFSCs using the same device, suggesting potential applications in human hair regrowth therapies. The study concludes that the microwell array device provides a promising method for the expansion of HFSCs, which could be beneficial for hair regrowth treatments.