Resequencing Analyses Revealed Genetic Diversity and Selection Signatures During Rabbit Breeding and Improvement

March 2024 in “ Genes ”

Kerui Xie, Chao Ning, Aiguo Yang, Qin Zhang, Dan Wang, Xinzhong Fan

TLDR Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.

The study utilized whole-genome resequencing to analyze genetic diversity and selection signatures in 180 rabbits from 17 breeds, identifying 17,430,184 high-quality SNPs. It revealed distinct genetic clusters among breeds and pinpointed genes linked to key traits such as coat color (TYR, ASIP), fur structure (LIPH), body size (INSIG2, GLI3), fertility (EDNRA, SRD5A2), heat stress adaptation (PLCB1), and immune response (SEC31A, CD86, LAP3). The findings highlight the genetic basis of phenotypic diversification in rabbits, aiding breeding programs and conservation efforts.

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Resequencing Analyses Revealed Genetic Diversity and Selection Signatures During Rabbit Breeding and Improvement

Research cited in this study

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