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In this study, researchers created a detailed human skin cell atlas by analyzing over 700,000 cells, finding that disrupted communication among specific immune and stromal cell subsets may play a key role in initiating and sustaining chronic skin inflammation in atopic dermatitis.

In this study involving genetically modified rats, researchers observed that specific mutations in the vitamin D receptor affect calcium levels and bone formation, emphasizing the receptor's role in maintaining healthy bone density and its importance in regulating hair cycle and skin health.

This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.

This review discusses the regulatory roles of type 2 alarmin cytokines in skin immunity, focusing on their implications in host defense, chronic inflammation, and cancer, but reports no new clinical results.

This review discusses the interactions between immune cells and the skin epithelium and their impact on maintaining barrier function, emphasizing the potential to enhance epithelial barrier function in inflammatory diseases.

This study observed that vitamin D therapy may help manage alopecia areata, totalis, and universalis, with promising hair regrowth in some pediatric cases, though further trials are needed.

This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.

This study found that alopecia in hereditary resistance to 1,25(OH)2D may indicate a more severe form of the condition, associated with earlier diagnosis and different responses to calciferol therapy.

This study found that holding abatacept infusions for four weeks or longer before elective hip or knee arthroplasty did not reduce the risk of post-operative infections or readmissions.

This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.

This study found that adding calcitriol to metformin significantly improved symptoms in patients with polycystic ovary syndrome and decreased serum MCP-1 levels compared to metformin alone.

This study found that localized skin calcification could be induced in adult rats through dihydrotachysterol treatment combined with topical trauma, offering an experimental model for calcifying scleroderma.

This study found that sodium selenite toxicity in cow calves significantly affects clinical and hematological parameters, with differing symptoms observed between subacute and chronic exposure.

This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.

This study found that calcium, magnesium, and vitamin D supplementation altered hair calcium and magnesium content in perimenopausal women, suggesting an early indicator of metabolic changes linked to skeletal mineralization.

This study reports that the homeopathic drugs Lycopodium clavatum and Calcarea carbonica showed significant ameliorative effects on polycystic ovarian syndrome symptoms, with some differences in individual symptom response.

In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.

In this study, two dialysis patients with high plasma silicon levels exhibited symptoms like painful skin eruptions and unusual hair growth, suggesting silicon may influence calcium metabolism similarly to aluminum.

This study found that sodium selenite induced both subacute and chronic selenosis in cow calves, significantly affecting specific haematological parameters, with more pronounced alterations observed in chronic toxicity.

This study found that applying BPM 31543 twice daily was safe, well-tolerated, and showed signs of reducing chemotherapy-induced alopecia in women receiving taxane-based chemotherapy.

Hair can show daily calcium changes, linked to body calcium levels and influenced by hormones, and can help assess calcium metabolism issues.

In this study, twice daily application of 3 μg/g calcitriol ointment was reported to be safe, effective, and well tolerated for treating moderate to severe chronic plaque psoriasis on the face and surrounding areas.

In their 1957 study, Neuman and Neuman suggested that magnesium deficiency may inhibit the ion exchange process required for calcium ions to enter extracellular fluid, potentially affecting calcium mobilization.

In this study, perimenopausal women with initially high hair concentrations of calcium, magnesium, and silicon experienced a decrease in these elements after intermittent dietary supplementation with calcium, magnesium, silicon, and vitamin D.

This historical observation found that parathyroid extract treatment in newborn rats led to a condition resembling scleroderma, characterized by skin hardening, calcium deposition, and possible necrosis.

In this case study, calcitriol treatment led to improvement in scleroderma symptoms and partial hair regrowth in a 20-year-old girl after other treatments had failed.

In this study, the growth-inhibiting potential of calcipotriol did not affect the telogen/anagen hair ratio during treatment for scalp psoriasis.

This study found that during dialysis, lower plasma-potassium levels were associated with hyperglycemia, suggesting potassium correction is vital when using glucose-rich dialysate.

This Phase 1 study reported that topical application of BPM31543 was safe and well-tolerated in patients receiving taxane-based chemotherapy, with some experiencing less than 50% hair loss, suggesting potential efficacy in reducing chemotherapy-induced alopecia, although no maximum tolerated dose was identified.