Silicon-Related Syndrome In Dialysis Patients

    January 1997 in “ Nephron
    Leopoldo F. Saldanha, Harvey C. Gonick, Hector J. Rodriguez, Jeffrey A. Marmelzat, Eliseo V. Repique, Cathy L. Marcus
    Studysummary In this study, two dialysis patients with high plasma silicon levels exhibited symptoms like painful skin eruptions and unusual hair growth, suggesting silicon may influence calcium metabolism similarly to aluminum.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The report described two dialysis patients with significantly elevated plasma silicon levels and a presumed silicon-related syndrome, presenting symptoms such as transient hypercalcemia, painful nodular skin eruptions, and aberrant hair growth. A study of 30 dialysis patients showed moderately elevated plasma silicon levels compared to normal controls, suggesting ingestion of silicon through foods and fluids as the source. The findings indicated a weak correlation between plasma silicon and serum calcium, suggesting that silicon might affect calcium metabolism similarly to aluminum.
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