10 citations
,
February 2017 in “Hormone Molecular Biology and Clinical Investigation” This randomized clinical trial found that vitamin D supplementation did not significantly alter anthropometric or metabolic parameters in obese, insulin-resistant, and vitamin D-deficient women with polycystic ovary syndrome, whereas metformin effectively reduced body weight, BMI, waist circumference, total body fat, and serum glucose levels.
October 2018 in “Annals of oncology” This study reported that topical BPM31543 was safe and well-tolerated for patients on taxane-based chemotherapy, with some efficacy indicated in reducing hair loss at all dosages tested.
2 citations
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May 2016 in “Journal of Clinical Oncology” This study found that topical BPM31543 was safe, tolerable, and showed potential to reduce chemotherapy-induced alopecia at higher dosing levels among adult women with cancer receiving taxane-based chemotherapy.
2 citations
,
December 1973 in “Calcified tissue research” This study proposed a hypothesis for cutaneous calcinosis, suggesting that feeding DHT and subsequent epilation lead to ATP release and calcium orthophosphate formation, initiating calcification in rats.
May 2003 in “Journal of clinical oncology” The authors of this study concluded that higher calcium levels in hair may indicate early metabolic changes leading to osteopenia or osteoporosis in menopausal women, even before detectable by standard DEXA imaging.
39 citations
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January 2017 in “Dermatologic Therapy” This study found that topical calcipotriol lotion resulted in hair regrowth in 59.1% of alopecia areata patients, with better response observed in those with lower serum vitamin D levels.
December 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that redhaired individuals consistently had higher calcidiol levels compared to non-redhaired subjects, suggesting a physiological adaptation for vitamin D synthesis in low UV-B conditions.
7 citations
,
January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
5 citations
,
July 2014 in “Journal of X-Ray Science and Technology” This study suggests that hair analysis could serve as a diagnostic tool for detecting calcium channel activity, which influences hair calcium levels and may indicate calcium deficiency or related disease states.
16 citations
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May 2006 in “The Journal of Dermatology” This study reported successful treatment of peeling skin syndrome using topical calcipotriol.
6 citations
,
March 2018 in “Proceedings - Baylor University. Medical Center” This case report describes a patient with sarcoidosis who experienced severe symptomatic hypercalcemia, scarring alopecia, and acute-on-chronic kidney failure.
14 citations
,
October 2016 in “Physiological Research” In this study, vitamin D supplementation showed no significant effect on androgen levels or clinical hyperandrogenism in PCOS women, but when combined with metformin, it improved testosterone levels.
18 citations
,
March 2016 in “Journal of Investigative Dermatology” This study found that calbindin-D9k knockout mice on a maternal vitamin D-deficient and low-calcium diet developed transient alopecia, but a high-vitamin D and calcium diet in mothers reduced this effect.
4 citations
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December 1962 in “European journal of endocrinology” Alloxan diabetes, methylthiouracil, cortisone, and adrenaline affect how white mice hair follicles use glucose and cystine and their cell division.
4 citations
,
September 1944 in “The American Journal of the Medical Sciences”
April 2025 in “International Journal of Homoeopathic Sciences” This case report describes marked improvement in symptoms for a 24-year-old woman with PCOS following individualized homeopathic treatment, which reportedly included a reduction in irregular menstruation, vaginal discomfort, and weight gain.
January 2018 in “Journal of Crohn s and Colitis” This study found that high-dose intravenous ferric carboxymaltose may reduce inflammatory activity in patients with inflammatory bowel disease and iron deficiency anaemia, as evidenced by decreased CRP levels and improved clinical disease indices.
In this retrospective study, all-female patients with iron deficiency anemia treated with ferric carboxymaltose experienced rapid symptom resolution and increased ferritine and hemoglobin levels, with some reporting manageable side effects such as rash and headache.
11 citations
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May 1985 in “Archives of Dermatology” This study found that calcitriol-resistant rickets is associated with alopecia in children and should be considered in the differential diagnosis of hair loss.
September 2024 in “Journal of the American Academy of Dermatology” Early intervention is important for limited systemic sclerosis patients due to higher pain and ulceration risks.
38 citations
,
May 1982 in “PubMed” This report describes almost complete resolution of calcinosis and healing of associated ulcers in an 83-year-old woman with localized scleroderma after repeated intralesional steroid injections.
55 citations
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May 1985 in “Archives of Dermatology” This study found that alopecia in four children was linked to severe calcitriol-resistant rickets, suggesting this condition should be considered among inherited hair growth disorders.
February 1977 in “Archives of Dermatology” This communication discusses previous reports of deadly hematopoietic depression associated with the topical use of demecolcine for skin cancers, highlighting potential hazards relative to colchicine ointment in psoriasis.
9 citations
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June 2020 in “European Radiology Experimental” This study found that single-dose x-ray irradiation in rat calvaria skin led to morphological changes in collagen fibers, disorganization, and a temporary absence of sebaceous glands and hair follicles.
4 citations
,
January 1998 In this study, higher concentrations of CaCl2 and specific inhibitors were found to inhibit the growth of seed roots and root hairs, but these effects could be reversed with certain treatments.
July 2014 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that low levels of calcium and magnesium in blood serum were associated with health issues like hair loss and anxiety among participants from urban and rural Pakistan.
September 2023 in “Environmental health perspectives. Supplements” This study found that children in Alcalá may have lower exposure to calcium and strontium compared to peers in other regions, based on scalp-hair analysis.
1 citations
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January 2007 in “Journal of Obesity & Metabolic Syndrome” A higher calcium to magnesium ratio in hair is linked to lower insulin sensitivity.
170 citations
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May 1979 in “The journal of pediatrics/The Journal of pediatrics” This report describes two sisters with rickets and alopecia unresponsive to high doses of vitamin D2, where oral phosphorus supplements led to significant clinical improvement.