Calcitriol-Resistant Rickets With Alopecia

May 1985 in “ Archives of Dermatology ”

Hochberg Z

calcitriol alopecia rickets cytoplasmic receptors nuclear receptors vitamin D hair follicles hair loss baldness

TLDR Calcitriol-resistant rickets is an inherited disorder that affects hair growth and causes hair loss.

The document discussed a study involving four children from two families who exhibited alopecia and severe rickets that were resistant to treatment. This condition was linked to defective cytoplasmic and nuclear receptors for calcitriol, the active form of vitamin D. Despite the alopecia, scalp biopsies showed a normal number of hair follicles with typical microscopic features. The study suggested that calcitriol-resistant rickets should be considered an inherited disorder affecting hair growth and highlighted the importance of considering the association of rickets with alopecia in diagnosing hair loss.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 100 upvotes 5 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 2 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

community Using topical vitamin D, does it make sense?

in Chat 5 upvotes 3 years ago

Topical Calcipotriol (vitamin D derivative) may help with hair regrowth, especially for alopecia areata. The user wonders if adding classic vitamin D to lotions like Minoxidil could have a similar effect.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 412 upvotes 8 months ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 43 upvotes 10 months ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community Second shed and more abnormalities

in Treatment 1 upvotes 1 year ago

The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

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research Adolescent Androgenic Alopecia: Pathophysiology, Diagnosis, and Treatment

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