High-Dosed Intravenous Iron Replacement Therapy Does Not Hinder Drug-Induced Amelioration of Disease Activity in IBD Patients with Iron Deficiency Anemia

    January 2018 in “ Journal of Crohn s and Colitis ”
    Jürgen M. Stein, S Vollmer, W Klemm, Nip Kerry, S Weber-Mangal, Axel Dignaß
    TLDR High-dose intravenous iron therapy doesn't interfere with treatment improvements in IBD patients with iron deficiency anemia.
    This study assessed the impact of high-dosed intravenous ferric carboxymaltose (FCM) on inflammatory activity in 224 IBD patients with iron deficiency anaemia across 101 centers in Germany. Over approximately 12 weeks, patients received a mean total FCM dose of 1139 mg. The study found that high-dosed FCM did not hinder drug-induced improvement of disease activity. Significant reductions in CRP levels indicated decreased inflammation, and improvements were observed in clinical disease indices (CDAI/CAI) and symptoms such as fatigue and hair loss. The therapy was effective regardless of baseline hemoglobin levels, and patients showed increased hemoglobin, serum ferritin, and transferrin saturation, with reduced CRP levels and symptoms.
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      community almost 6 months of progress :)

      in Progress Pictures  535 upvotes 11 months ago
      The user shared their 6-month hair regrowth progress using finasteride, minoxidil, biotin, and iron supplements, along with occasional microneedling and specific shampoos. They reported minimal side effects and no retrograde alopecia, attributing their success to a combination of treatments.

      community how did i do? around 4 months of progress

      in Is this regrowth?  250 upvotes 1 year ago
      The user experienced hair regrowth using finasteride, minoxidil, biotin, iron, microneedling, and caffeine shampoo over four months. They plan to continue treatment for fuller results by month 6 or 7.

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