TLDR Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.
In a study of 93 IBD patients treated with anti-TNFs, 6.45% developed severe psoriasiform reactions, necessitating the withdrawal of the treatment. Two patients (2.5%) developed alopecia universalis, with one having a history of alopecia areata, suggesting a potential risk factor. Ustekinumab was found to be an effective alternative for managing these adverse effects. Additionally, a case of molluscum contagiosum was resolved with podophyllin and cessation of immunosuppressive therapy.
1 citations
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August 2023 in “Acta dermato-venereologica” Corticosteroids are the most common treatment for alopecia areata, but many patients need better options.
6 citations
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December 2022 in “Journal of autoimmunity” JAK inhibitors like tofacitinib may effectively treat Alopecia Areata.
October 2022 in “Journal of Armed Forces Medical College, Bangladesh” Tofacitinib is effective and safe for treating alopecia areata.
39 citations
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April 2016 in “Case Reports in Dermatology” Tofacitinib temporarily regrew hair in a man with alopecia, but its effects didn't last.
5 citations
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June 2015 in “Veterinary dermatology” A dog with complete hair loss regrew most hair after treatment, with no relapse after stopping treatment.
39 citations
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April 2003 in “Australasian journal of dermatology” PUVA treatment led to significant hair regrowth in over half of the patients with alopecia areata totalis and universalis.
