Clinical and Hematological Studies on Experimentally Induced Selenosis in Crossbred Cow Calves

The study investigated the effects of sodium selenite-induced subacute and chronic selenosis on clinical and hematological parameters in cross-bred cow calves. Subacute selenosis was induced with a dose of 2.5 mg/kg for 21 days, resulting in symptoms like anorexia, salivation, and joint swelling. Chronic selenosis was induced with 0.25 mg/kg for 16 weeks, leading to rough hair coat, alopecia, and hoof enlargement. Both forms of selenosis significantly impacted blood parameters such as hemoglobin, packed cell volume, and total erythrocyte and leukocyte counts, while chronic toxicity specifically altered mean corpuscular volume and hemoglobin. Erythrocyte sedimentation rate and mean corpuscular hemoglobin concentration were unaffected.