Oral Calcitriol in the Treatment of Scleroderma 'En Coupe De Sabre'

    January 2000 in “ Journal of Dermatological Treatment ”
    Bianca Maria Piraccini, Colombina Vincenzi, Sandra Lorenzi, Matilde Iorizzo, Antonellá Tosti
    TLDR Oral calcitriol helped improve scleroderma and hair regrowth in a young woman.
    A 20-year-old girl with rapidly progressing linear scleroderma on her forehead and scalp, which included linear alopecia and a bone depression in the parietal skull, did not respond to hydroxychloroquine and systemic steroids. However, treatment with oral calcitriol at 0.75 µg/day for 12 months led to a prompt resolution of perilesional erythema, gradual thinning of the scleroderma band, and partial hair regrowth.
    Discuss this study in the Community →