Multi-Modal Skin Atlas Identifies a Multicellular Immune-Stromal Community Associated with Disrupted Cornification and Specific T Cell Expansion in Atopic Dermatitis

    February 2026 in “ Nature Communications ”
    Evgenij Fiškin, Gökcen Eraslan, Maria B. Alora-Palli … Ramnik J. Xavier
    Studysummary In this study, researchers created a detailed human skin cell atlas by analyzing over 700,000 cells, finding that disrupted communication among specific immune and stromal cell subsets may play a key role in initiating and sustaining chronic skin inflammation in atopic dermatitis.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on doi.org →
    Discuss this study in the Community →

    Research cited in this study 1

    1. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations Journal of Investigative Dermatology · 2018