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This study explored the effects of a 50% hydroalcoholic UPBF extract on BPH in testosterone propionate-induced rats, finding significant improvements in prostate-related parameters and lower urinary tract symptoms at a 200 mg/kg dose, suggesting potential use in BPH management.

This study found that specific TRPM5 modulators are unlikely to directly affect sebaceous glands, but safe TPPO analogues may provide moderate lipogenic and anti-inflammatory effects beneficial for dry skin conditions.

This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.

In this review, researchers highlighted that natural polyphenolics like flavonoids and resveratrol may help enhance testosterone production in aging males by boosting the expression of the Star gene in Leydig cells, potentially preventing age-related degenerative conditions linked to testosterone insufficiency.

This study examined the latest advances in synthetic biology for increasing microbial production of sesquiterpenol compounds, highlighting innovative strategies to overcome challenges such as low yields and terpenoid-related toxicity, which hinder industrial-scale applications.

This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.

This study found that the chemical composition and biological activity of Platycladus orientalis fruit extracts varied with the extraction method, revealing potent antioxidant and enzyme inhibitory properties, particularly in the n-hexane extract, which suggests potential applications for managing dysregulated enzyme conditions.

This study found that Ocimum basilicum L. showed the highest 5α-reductase inhibitory activity among ten Thai plants, despite no correlation between enzyme inhibition and total phenolic content.

This study found that apocynin restored collagen production, reduced DNA damage and senescence, and protected skin stem cells from aging in UVB-exposed human keratinocytes.

This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.

This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.

This study found that a mixture of plant extracts significantly improved skin barrier function, reduced inflammation, and exhibited anti-aging effects in human skin cells.

This study investigated the phytochemicals in Phyla nodiflora leaf extracts and identified n-Hexadecanoic acid, stigmasterol, and beta-sitosterol as promising drug candidates for diabetes, alopecia, cancer, and anti-diuresis, advocating further research into these compounds.

This study found that L-borneol, derived from Chinese medicine, significantly promotes the differentiation of rat hair follicle stem cells into basal layer cells, aiding wound healing, with the process involving inhibition of the PODXL2 gene by the microRNA rno-miR-127.

In this study, the combination of Serenoa repens extract with Phenolmicin P3 and Bosexil suppositories significantly improved lower urinary tract symptoms and decreased PSA levels in patients with benign prostatic obstruction-related symptoms.

In this study, the synthesis of C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone revealed an unexpected formation of a C-4 substituted product using a 6-bromo derivative, contrary to prior reports.

This study examined finasteride degradation under stress conditions, identifying three unique degradation products in acidic environments, providing insights into impurity profiling and quality control for finasteride formulations.

This study found that a hair-coating polyphenol complex significantly enhanced the mechanical strength, UV protection, and antistatic properties of damaged hair, suggesting potential benefits for hair treatment.

This study established a sensitive and reproducible method for determining the levels of four organic solvents in finasteride raw materials, meeting the requirements of the Chinese Pharmacopeia.

This study suggests that geranyl acetate may offer protective, anti-inflammatory, and cytoprotective effects against PPD-induced toxicity in keratinocyte cells, indicating its potential as a plant-derived treatment.

This study assessed the antioxidant properties and contents of carotenoids and chlorophylls in 10 plant oils, finding fenugreek seed oil to be highest in carotenoids and pomegranate oil most active against free radicals, highlighting their potential as natural materials with antioxidant benefits.

This study comparatively evaluated different extraction techniques for Schinus terebinthifolius Raddi leaf extracts and found that conventional extraction with ethanol yielded the highest antioxidant activity and beneficial effects on skin cell viability, supporting its potential use in sustainable cosmeceutical formulations targeting skin aging.

This study developed an efficient method for converting polymeric procyanidins into high-purity oligomeric procyanidins using a semisynthetic approach combined with separation techniques.

This study found that BEO inhibited cell proliferation and inflammatory mediator release in a human keratinocyte acne model and reduced acne lesion severity in a rabbit model, suggesting its potential as a natural alternative to conventional acne treatments.

This study isolated highly pure oleanolic and maslinic acids from olive milling residues, exploring their chemical reactions, including the formation of finasteride precursors.

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.

This review discusses the pharmacological effects and potential mechanisms of procyanidins, noting its roles in antioxidation, cardiovascular protection, and more, but reports no new clinical results.

This review reports that herbal cosmetics offer diverse biological benefits, including antioxidant, antibacterial, and moisturizing effects, enhanced by advanced formulation methods, while emphasizing the need for more clinical validation and standardized practices to ensure long-term safety and efficacy.

This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.