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This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.

This study found that biotransformation of finasteride by Aspergillus niger produced two metabolites with different levels of lipoxygenase inhibition, suggesting potential for developing more potent derivatives.

This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.

In this study, researchers synthesized biomedical polyurethanes incorporating curcumin and varying PEG content to enhance water solubility and control curcumin release, finding that higher PEG content improved hydrophilicity, swelling, and degradation, while maintaining excellent antioxidant and antibacterial activities, suggesting promise for biomedical applications.

In this study, researchers found that the conventional solvent extraction method yielded the highest polyphenol content and antioxidant activity from Ascophyllum nodosum seaweed on Québec's North Shore.

This study found that Melamax®, originally developed as an eco-friendly hair dye, provides significant protection against ultraviolet-induced oxidative and inflammatory damage in keratinocytes by modulating gene expression and signaling pathways, highlighting its dual potential for cosmetic coloration and skin photoprotection.

This study found that certain molecular quantum descriptors can be directly correlated with the biological activity of benzo[c]quinolizin-3-ones, potentially aiding in the identification and design of active compounds.

This study developed a protocol for callus induction and found that certain hormone concentrations enhance the production of flavonoids, phenols, and terpenes in Bituminaria bituminosa.

Brunfelsia uniflora has good antioxidant properties and moderate antibacterial activity.

This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.

This study found that biliverdin beta and delta, metabolites of heme, play a critical role in Pseudomonas aeruginosa iron acquisition and cooperative behaviors, which are crucial for the bacterium's long-term infection in cystic fibrosis patients, suggesting potential targets for new therapies.

This study found that forming inclusion complexes of DPCP with HPβCD using the 3D ground mixture method enhances its anti-inflammatory activity at lower doses compared to complexes with β-CD.

This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.

In this study, extracts from the bark of Albizia saponaria, particularly the ethyl acetate fraction, showed significant antioxidant activity, potentially due to its high phenolic and flavonoid content, suggesting its usefulness as a source of antioxidants for pharmaceutical formulations.

In this study, researchers using advanced chromatography and mass spectrometry techniques tentatively identified 132 chemical compounds in Justicia procumbens, including 54 lignans and 77 compounds reported for the first time, which may aid in pharmacological research and quality control of the plant.

This study in humans and pigs found that finasteride metabolism is significantly influenced by CYP3A4, with induced metabolism decreasing and inhibited metabolism increasing plasma exposure of the drug.

This study found that pretreatment combining maceration with press-shear force and moist heat significantly increased the total phenolic and flavonoid contents in galactagogue herbs like banana inflorescences and Thai ginger.

In this study, methanolic extracts of Hibiscus rosa-sinensis showed higher phenolic and flavonoid content, as well as greater concentrations of gallic acid and quercetin, than aqueous extracts, despite the latter yielding more extract, highlighting the effectiveness of methanol for extracting bioactive phytochemicals.

This study found that phenolic compounds from Quercus acutissima, particularly casuarinin, showed strong antioxidative, anti-inflammatory, and antiacne effects in mouse macrophage cells, suggesting potential therapeutic candidates for acne.

This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.

This study identified novel compounds as selective inhibitors of the type 1 isoenzyme of 5α-reductase, displaying promising potential for treating DHT-dependent disorders such as acne and androgenic alopecia.

This study evaluated a hair tonic formulated from oil palm leaf extract, finding it demonstrated very strong antioxidant activity and could prevent hair decolorization from sun exposure, with effective concentrations ranging from 25 to 200 ppm.

This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.

In this study, 4-(4-(phenylaminocarbonyl)benzoyl) benzoic acid exhibited the strongest inhibitory activity against the human type 2 steroid 5α-reductase isozyme among the compounds tested.

This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.

This study found that Gynostemma pentaphyllum hydrodistillate and Damulin B exert significant anti-photoaging effects in UVB-irradiated models by reducing oxidative stress, improving ECM integrity, and enhancing skin hydration and elasticity.

This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.