The Hair Loss Encyclopedia

An Analytical Framework for the Selective Extraction and Determination of Nine Multiclass Endocrine-Disrupting Chemicals from Haircare Products

June 2025 in “ Cosmetics ”

Ilaria Neri, Ritamaria Di Lorenzo, Giacomo Russo, Teresa Di Serio, Lucia Grumetto, Sonia Laneri

endocrine-disrupting chemicals parabens bis(2-ethylhexyl) phthalate dibutyl phthalate chromatographic method endocrine disruptors DEHP DBP

TLDR Haircare products may expose users to harmful chemicals despite regulations.

The study developed a chromatographic method to analyze nine endocrine-disrupting chemicals (EDCs) in haircare products, focusing on parabens, phthalates, and triclosan. Testing 26 products revealed that while paraben levels were within legal limits, dibutyl phthalate (DBP) was present in all samples, with concentrations ranging from 151.01 μg/100 g to 1042.58 μg/100 g. The method demonstrated high accuracy, with recovery rates between 66% and 87%. The study underscores the potential health risks of chronic EDC exposure through haircare products and emphasizes the need for routine monitoring and safer alternatives.

View this study on mdpi.com →

Discuss this study in the Community →

Research cited in this study

4 / 4 results

Revitalizing Effect on the Scalp After Injection with a Mechanically Stabilized Hyaluronic Acid Complex in Subjects with Androgenetic Alopecia

research Revitalizing Effect on the Scalp After Injection with a Mechanically Stabilized Hyaluronic Acid Complex in Subjects with Androgenetic Alopecia

November 2024 in “Journal of Clinical Medicine”

The treatment improved hair thickness, shine, and reduced hair loss effectively.

Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders

research Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders

14 citations , May 2022 in “Asian Journal of Pharmaceutical Sciences”

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

research Enhancing Permeation of Drug Molecules Across the Skin via Delivery in Nanocarriers: Novel Strategies for Effective Transdermal Applications

365 citations , March 2021 in “Frontiers in Bioengineering and Biotechnology”

Nanocarriers can improve drug delivery through the skin by overcoming barriers.

Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

research Transfollicular Drug Delivery: Penetration of Drugs Through Human Scalp Skin and Comparison of Penetration Between Scalp and Abdominal Skins In Vitro

82 citations , January 2002 in “Journal of drug targeting”

Drugs penetrate scalp skin better than abdominal skin, with scalp hair follicles aiding in higher drug delivery.