3 citations
,
January 2016 in “Chemical sciences journal” This study found that ethanol and petroleum ether extracts of Tridax procumbens roots demonstrated significant antibacterial activity against various bacterial strains compared to benzene extracts.
May 2015 in “HAL (Le Centre pour la Communication Scientifique Directe)” In this study, the stability properties of various active pharmaceutical ingredients (APIs) were characterized, revealing how factors like pressure and water sensitivity influence their intrinsic stability and potential degradation.
165 citations
,
July 1992 in “Annals of Internal Medicine” This editorial discusses the potential health risks of herbal preparations, highlighting a case of hepatotoxicity in a child due to pyrrolizidine alkaloids in a herbal tea; it reports no new results.
13 citations
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January 2019 in “Colloids and Surfaces B: Biointerfaces” This study found that incorporating a block copolymer significantly alters the size and morphology of niosome drug delivery systems made of non-ionic surfactants and cholesterol, affecting their stability.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
This chapter discusses phase transitions in various pharmaceutical examples and does not present any new research findings.
2 citations
,
January 2023 in “Plants” This study highlights the essential role of plant bioactive compounds in human health, attributing their beneficial effects to various biological activities such as antioxidant, anticarcinogenic, and antimicrobial actions, which can aid in preventing or managing noncommunicable diseases, including autoimmune and neurodegenerative conditions.
67 citations
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December 2019 in “PloS one” This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.
6 citations
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December 2020 in “Biological & Pharmaceutical Bulletin” This study found that certain fatty acids and triterpenoid-glycosides from Eclipta prostrata L. leaves exhibit potent inhibitory effects on the protein tyrosine phosphatase 1B enzyme, suggesting potential anti-diabetic and anti-obesity benefits.
December 2024 in “Plant Science Today” This study investigated the therapeutic potential of phytochemicals from Phyla nodiflora, identifying 50 bioactive compounds through GC-MS analysis. Among them, n-hexadecanoic acid, stigmasterol, and beta-sitosterol showed promise in molecular docking studies as drug candidates for diabetes, alopecia, cancer, and anti-diuresis.
31 citations
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February 1972 in “Experientia” This study found that the diphosphonate ethan-1-hydroxy-1,1-diphosphonat was the most effective compound in preventing calcifications in rats induced by DHT, compared to other phosphatase inhibitors and polyphosphates tested.
22 citations
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June 2021 in “Plants” This study found that a methanolic extract of Sterculia foetida seeds demonstrated significant thrombolytic, anti-arthritic, analgesic, and antipyretic activities, with moderate cytotoxic effects in vitro and in vivo.
3 citations
,
June 2020 in “Pharmacognosy Journal” In this study, researchers developed ethosomes containing Phyllanthus emblica extract and found them to have beneficial properties, including high entrapment efficiency and antioxidant activity, suggesting potential as an alternative product for preventing hair loss.
50 citations
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May 2019 in “BioFactors” This review discusses the impact of air pollution on skin health and suggests that targeting oxidative stress products like HNE could be a new strategy for treating related skin conditions.
1 citations
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June 2025 in “Pharmacognosy Research” This study found that a polyherbal sunscreen cream, F4, containing Camellia sinensis, Vitis vinifera, and Silybum marianum extracts demonstrated strong antioxidant and photoprotective properties, similar to synthetic sunscreens.
1 citations
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January 2006 in “Maia-rivista Di Letterature Classiche” This review discusses the bioactive compounds and biological activities of Polygonum multiflorum Thunb. and highlights concerns about its hepatotoxicity, but reports no new clinical results.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that herbal cosmetics, incorporating modern technologies and traditional knowledge, offer various biological benefits like antioxidant and anti-aging properties. The authors emphasize the need for further clinical validation and standardized manufacturing processes to ensure their long-term safety and effectiveness.
20 citations
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February 2022 in “Pharmaceutics” This study found that idebenone-loaded nanoparticles (IB@NPs) improved stability, antioxidant activity, and wound healing capacity in vitro, suggesting potential applications in cosmetic and pharmaceutical fields.
7 citations
,
March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
16 citations
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October 2009 in “Xenobiotica” This study found no evidence that the tested hair dye ingredients undergo hepatic metabolism to reactive oxidized metabolites in human liver microsomes and hepatocytes.
5 citations
,
January 1994 in “PubMed” This study found that the metabolism of finasteride in rat hepatic microsomes involves key hydroxylation steps, highlighting the role of a novel enzyme in 6 alpha-hydroxylation.
49 citations
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April 2003 in “Biomaterials” In this study, BS and BO combined showed a synergistic effect in enhancing wound healing in rat skin lesions compared to using either alone or Flamazine®.
14 citations
,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
8 citations
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November 2015 in “Saudi Journal of Biological Sciences” This study found that KH053, combining Panax ginseng and bee-pollen, significantly reduced prostate weight and DHT levels, inhibiting BPH development in a rat model.
8 citations
,
January 2012 This review compiles scientific evidence on the effects of green tea polyphenols on cosmetic issues like aging and acne, but reports no new clinical results.
35 citations
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October 2005 in “European journal of pharmaceutics and biopharmaceutics” This study found that polymers significantly improved the chemical and microbial stability of steroid hormones in liposome formulations over eight weeks, with finasteride showing the highest diffusion rate.
February 2026 in “International Journal of Molecular Sciences” This study investigated the photoprotective properties of Brazilian pepper tree extract against UV-induced damage in skin cells, reporting that it enhanced expression of genes relevant to skin health and showed superior activity compared to standard antioxidants.
November 2023 in “Journal of the American Academy of Dermatology” This study explored spontaneous repigmentation after phenol-croton oil peels in skin of color, finding that temporary hypopigmentation resolved by day 21 in both a black-skin domestic pig model and human clinical observations, highlighting potential for these procedures despite past concerns about pigmentation issues.
4 citations
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January 2018 in “Cosmetics” This review discusses the potential use of spin traps in cosmetic products to limit reactive oxygen species generated by pollution, emphasizing the need for further research due to toxicity and regulatory concerns.
January 2002 in “Chinese Journal of Pharmaceuticals” This study reports the preparation of a key intermediate for finasteride and epristeride with a 69% overall yield from pregnenolone acetate.