Formulation And Characterization Of A Polyherbal Sunscreen Containing Camellia Sinensis, Vitis Vinifera, And Silybum Marianum Extracts

June 2025 in “ Pharmacognosy Research ”

J. Nandhini, Sumithra Arumugam, Balan Paramasivam, Saravanan Govindasamy Kuppusamy, J. Saravanan, Parthasarathi Venkateasan, Sankaran Rajendran, Karthikeyan Elumalai

Camellia sinensis Vitis vinifera Silybum marianum polyherbal sunscreen antioxidant photoprotective reactive oxygen species Sun Protection Factor UV-induced skin damage green tea extract grape seed extract milk thistle extract SPF UV protection

TLDR The F4 polyherbal sunscreen is a promising natural alternative with effective UV protection and antioxidant benefits.

The study developed a polyherbal sunscreen cream containing extracts from Camellia sinensis, Vitis vinifera, and Silybum marianum, aiming to provide antioxidant and photoprotective benefits. Among six formulations, F4 showed superior performance with high release rates of active compounds and potent antioxidant activity, inhibiting 71.56% of reactive oxygen species. It achieved a Sun Protection Factor (SPF) of 25.38, comparable to synthetic sunscreens, and maintained stability over three months. F4 presents a promising natural alternative for protecting photosensitive individuals from UV-induced skin damage.

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