TLDR The new sunscreen cream is effective, safe, and has good skin qualities.
The study formulated a photoprotective cream with a new compound synthesized from p-aminosalicylic acid and 2,6-dichloroacetanilide, encapsulated in nanostructured lipid carriers to enhance efficacy and reduce toxicity. The cream included inorganic filters, natural products, and antioxidants, providing UVA and UVB protection, hydration, and anti-free radical benefits. Acute toxicity tests on 10 NMRI mice showed no significant adverse effects, confirming safety. The cream had stable physicochemical properties, a pH of 6.3, and maintained quality over 3 months. It demonstrated a satisfactory SPF of 16, good spreadability, and pseudoplastic flow behavior, effectively protecting skin from sunburn without irritation.
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