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5 / 20 resultslearn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Overview
learn Stem Cell Factor
Research
5 / 1000+ resultsresearch Study on the Formulation and Characterization of a Photoprotective Cream Containing a Newly Synthesized Compound
The study focused on developing a photoprotective cream using a newly synthesized organic sunscreen compound created from the condensation of sodium salt of p-aminosalicylic acid with 2,6-dichloroacetanilide. This compound was combined with metal oxides and various natural extracts to enhance its emollient, protective, and moisturizing properties. The compound was encapsulated into nanostructured lipid carriers to minimize the amount of UV filter needed. The resulting cream exhibited favorable skin application qualities, including appropriate pH, viscosity, and spreadability, and achieved a satisfactory SPF value of 16. The new compound was also shown to be non-toxic.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Influence of the Alkylsulfonylamino Substituent Located at the 6-Position of 2,2-Dimethylchromans Structurally Related to Cromakalim: From Potassium Channel Openers to Calcium Entry Blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Type 2 Diabetes Mellitus Inhibits Skin Renewal Through Inhibiting WNT-Dependent Lgr5+ Hair Follicle Stem Cell Activation in C57BL/6 Mice
Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
Community Join
5 / 1000+ resultscommunity My 2 year and 6 months progress. Finasteride 1 mg
A 31-year-old man shared his 2.6-year hair loss treatment progress, using 1 mg of finasteride daily, micro-needling every other week, and biotin vitamins, with no side effects and varying amounts of shedding. Other users discussed their own experiences with hair loss treatments, including the use of oral minoxidil and the long-term effectiveness of finasteride.
community Little to no results 6 months after 4000 grafts hair transplant. Should i wait longer? (i'm on fin, min, keta and biotin. No microneedling after HT)
Six months after a 4000 graft hair transplant, the individual has seen little to no results. They are currently using finasteride, minoxidil, ketoconazole, and biotin but not microneedling. The advice given is to wait another 2-6 months as full results can take up to a year, and to consider the possibility of shock loss.
community 26, 6 month progress on dut + min
The user shared their 6-month progress using oral dutasteride and minoxidil for hair loss, noting improvements without significant side effects. They currently use 0.5mg oral dutasteride, 5mg oral minoxidil, 5% topical minoxidil, and ketoconazole shampoo twice a week.
community 2.5 months topical minoxidil Progress
The conversation is about a user's hair regrowth after 2.5 months using topical minoxidil. Some suggest adding finasteride for long-term results, while others share their experiences with side effects or alternative treatments like dermarolling and dietary improvements.
community Studies show: 0.2 mg reduces scalp DHT by ~55%. 1 mg reduces it by ~64%. 5 mg reduces it by ~69%.
Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.