Identification and In-Silico Analysis of Phytochemicals from Phyla Nodiflora: Potential Bioactive Compounds for Therapeutic Applications

    December 2024 in “ Plant Science Today ”
    Prasanna Seenivasan, U Palanikumar, A. Thangavelu, R. Balasubramanian
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    TLDR Phyla nodiflora contains compounds that may help treat diabetes, alopecia, cancer, and anti-diuresis.
    The study investigates the therapeutic potential of phytochemicals from Phyla nodiflora, a medicinal plant, using in-silico analysis. Through GC-MS analysis, 50 chemical compounds were identified, with 10 predominant ones selected for further study. Molecular docking studies revealed that n-hexadecanoic acid, stigmasterol, and beta-sitosterol show significant potential as drug candidates for conditions like diabetes, alopecia, cancer, and anti-diuresis. These findings highlight the medicinal value of P. nodiflora and suggest further research, including in vitro and in vivo studies, to validate these compounds' efficacy, emphasizing the importance of plant-based drug discovery for non-communicable diseases.
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