Screening for Anti-Inflammatory Activities in Extracts from Korean Herb Medicines

    Sang Mi An, Hyoung Gun Kim, Eun Jung Choi, Hyoung Hoon Hwang, Eunseok Lee, Ji Hwoon Baek, Yong Chool Boo, Jae Sook Koh
    TLDR Some Korean herb extracts can reduce inflammation and are safe for skin use.
    The study investigated the anti-inflammatory activities of 51 Korean herb medicine extracts using RAW264.7 macrophage cells. Ten ethanol extracts, including those from Biotae Orientalis Folium and Dioscoreae Rhizoma, were found to reduce cytotoxicity and inhibit the production of inflammatory cytokines such as Nitric oxide, IL-1β, IL-6, and TNF-α in LPS-induced macrophages. These extracts did not cause skin irritation in human patch tests, suggesting their potential as cosmetic agents for preventing skin irritation.
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