Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants
June 2024
in “
Nutrients
”
polyphenolic antioxidants flavonoids resveratrol phenolic acids testosterone production steroidogenic acute regulatory protein STAR gene Leydig cells androgen biosynthesis steroidogenic enzyme activities hypothalamus-pituitary gland axis testosterone bioavailability luteolin quercetin ferulic acid phenethyl ester gigantol polyphenols testosterone STAR androgens hormone production hormone bioavailability
Studysummary In this review, researchers highlighted that natural polyphenolics like flavonoids and resveratrol may help enhance testosterone production in aging males by boosting the expression of the Star gene in Leydig cells, potentially preventing age-related degenerative conditions linked to testosterone insufficiency.
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