Study of the Reactivity of the A and C Rings of Natural Olean-12-enes for the Obtaining of Chiral Synthons

    January 2003 in “ Dialnet (Universidad de la Rioja)
    Yolanda Simeó Ocaña
    TLDR The study found ways to create important compounds for male health from olive waste.
    The study focused on the reactivity of the A and C rings of natural olean-12-enes, derived from triterpenic compounds found in olive milling residues. The research was divided into three main parts: examining the reactivity of the C ring through the formation of derivatives like sulfates and epoxides, studying oxidative processes affecting the C ring, and fragmenting the olean-12-ene molecule to obtain sesquiterpenic fragments with biological interest. The study highlighted the formation of finasteride synthons, a compound important for treating male disorders, derived from contracted A ring compounds.
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