Study of the Reactivity of the A and C Rings of Natural Olean-12-enes for the Obtaining of Chiral Synthons

    January 2003 in “ Dialnet (Universidad de la Rioja) ”
    Yolanda Simeó Ocaña
    TLDR The study found ways to create important compounds for male health from olive waste.
    The study focused on the reactivity of the A and C rings of natural olean-12-enes, derived from triterpenic compounds found in olive milling residues. The research was divided into three main parts: examining the reactivity of the C ring through the formation of derivatives like sulfates and epoxides, studying oxidative processes affecting the C ring, and fragmenting the olean-12-ene molecule to obtain sesquiterpenic fragments with biological interest. The study highlighted the formation of finasteride synthons, a compound important for treating male disorders, derived from contracted A ring compounds.
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