Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.

This study presented a new two-dimensional model that successfully predicts transdermal permeation of caffeine, highlighting the significant role of the follicular pathway in increasing systemic bioavailability.

This review highlights cobalt's essential role in vitamin B12 metabolism and its biomedical applications but also warns of health risks from high levels and environmental contamination, discussing remediation methods like phytoremediation.

This review evaluates recent advances from 2016 to 2022 in the use of microbubbles and nanobubbles, highlighting their potential for safer diagnostic and therapeutic applications in radiology and medicine without the side effects associated with traditional methods.

This study introduced a new spectrofluorometric method using a synthesized organic fluorophore to effectively analyze darolutamide and thalidomide in pharmaceutical preparations and biofluids.

This study found that domestic temporary hair dyes may pose a health risk due to their cytotoxic effects on human red blood cells and NIH/3T3 cell lines.

In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.

This study developed a new spectrophotometric method to accurately measure finasteride levels in pharmaceutical formulations using a reaction with NBD-CL.

This study concluded that the test and reference finasteride tablets were bioequivalent in terms of pharmacokinetic parameters in healthy male volunteers.

In this study, chaconine, solanine, solamargine, and solasonine were found to inhibit cucumber root growth, while their 6-O-sulfated derivatives had no effect, highlighting the importance of carbohydrate moieties in this process.

This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.

This study found that two finasteride preparations were bioequivalent in human volunteers when tested using a new HPLC method for pharmacokinetics.

In this study, researchers documented the immunohistochemical distribution of CD34 in basal cell carcinoma and found distinct patterns of CD34 expression, with variations in CD34 positivity between different areas of BCC tumor stroma and adjacent skin regions.

This study examined the role of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

This study reported that while general patient characteristics and adverse event incidence for eribulin were comparable between a healthcare claims database and post-marketing surveillance, significant differences in some side effects such as neutropenia were observed.

This study found that a 30 Gy radiation dose was most effective in an experimental rabbit model of radiodermatitis, causing significant tissue changes and prolonged effects compared to lower doses and a control group.

This study evaluated methods to administer betulin in in vivo experiments and found that olive oil, food-grade lard, and other carriers increase betulin absorption in Wistar rats, while monitoring blood levels may aid future clinical research.

This study found that blood and milk somatic cells show promise as matrices for monitoring illicit recombinant bovine somatotropin use in dairy cattle through gene-expression assays.

The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.

This study demonstrates a method to noninvasively assess lipid classes in rodent sebum via high-field proton NMR, observing significant lipid reductions in rats treated with an SCD1 inhibitor.

This study found that the pharmacokinetic profile of finasteride capsules and tablets in healthy volunteers is bioequivalent.

This study discovered that the disposition of LY191704 enantiomers in rats and dogs is both stereoselective and species specific.

In this first-in-human study, BLZ-100, an intraoperative fluorescent imaging agent, was administered to 21 patients before skin cancer surgery and was found to be well tolerated without serious adverse effects, suggesting its potential to help distinguish cancerous from non-cancerous tissue based on fluorescence.

This study analyzed dosimetric quantities in x-ray microbeam radiation therapy and found that the peak-to-valley dose ratio decreases with depth in the irradiated object.

This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.

This case report describes a six-year-old child with congenital biotinidase deficiency whose symptoms, including breathlessness, alopecia, and hearing loss, were reversed with biotin supplementation.

This study found that domestic finasteride tablets are bioequivalent to reference tablets, showing similar pharmacokinetic parameters and relative bioavailability.

This review covers the molecular basis of Birt–Hogg–Dubé syndrome and its implications for potential therapeutic targets, but it does not report new experimental results.