10 citations
,
November 2017 in “Letters in drug design & discovery” This paper discusses a structure-based analysis to find new BRD4 inhibitors, identifying finasteride and amentoflavone as promising candidates for BET inhibition.
6 citations
,
January 2013 in “Experimental dermatology” This study found that bimatoprost, when applied daily at a 0.03% concentration, promoted significant hair growth in C57/black 6 mice, including earlier and faster regrowth of shaved fur.
January 2018 in “Computational Toxicology” This review introduces pharmacophore technology and discusses its applications in toxicity prediction and limits, but reports no new clinical results.
1 citations
,
July 2018 in “Dermatologic Surgery” This article outlines the scope and content of the Dermatologic Surgery journal, providing an overview without reporting new research results.
October 2023 in “Pharmacoepidemiology and Drug Safety” This study found that in Denmark, dermatology drugs are mostly used as expected, but identified a few unexpected patterns that warrant targeted follow-up to determine if there is inappropriate use.
67 citations
,
May 2013 in “Therapeutic drug monitoring” This study explores the complexities of interpreting single drug exposure in hair, emphasizing factors like drug distribution variability and suggests methods to validate single exposure findings in forensic cases.
January 2016 in “Institutional Repositories DataBase (IRDB)” This study examined the expression of fatty acid transporters and binding proteins in mouse sebaceous glands and found that CD36 did not affect the localization of other related molecules.
5 citations
,
May 2019 in “Cureus” In this study, the authors reported that taking 20 mg or more of biotin can interfere with thyroid function tests, potentially leading to false diagnoses of conditions like Grave's disease.
136 citations
,
April 2013 in “Clinical Cancer Research” The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
8 citations
,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” This study suggests that in rat skin, testosterone itself may play a more significant role in androgen action than 5α-dihydrotestosterone, unlike in the prostate where 5α-DHT is more dominant.
September 2018 in “Facial Plastic Surgery Clinics of North America” Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.
January 2019 in “International journal of medical biochemistry/International journal of medical biochemistry :”
1 citations
,
August 2018 in “International Journal of Research -GRANTHAALAYAH” This review discusses the history and development of techniques for detecting bioelectromagnetic emissions in living tissue and reports no new experimental results; potential medical applications are explored.
1 citations
,
July 2005 in “CRC Press eBooks” This paper discusses topical drug delivery targeting the pilosebaceous unit for skin diseases and cosmetic purposes, emphasizing formulation choice and drug physicochemical properties but reports no new findings.
January 2006 in “Analytical chemistry, an Indian journal” This study developed two sensitive spectrophotometric methods to accurately determine finasteride in pure and tablet forms, demonstrating linear response and compliance with ICH guidelines.
4 citations
,
July 2023 in “Analytical and Bioanalytical Chemistry” 3 citations
,
April 2023 in “Cytotechnology” 1 citations
,
September 1993 in “Archives of Disease in Childhood” This article discusses the importance of considering biotinidase deficiency in differential diagnosis for patients with certain neurological and dermatological symptoms, as timely treatment with biotin is crucial to prevent severe consequences.
1 citations
,
March 2024 in “Life” In this study, researchers identified specific clinical and dermoscopic features of chronic radiation-induced dermatitis in 32 head and neck cancer patients treated with radiotherapy, and determined age, gender, and prior surgery as independent risk factors for developing this skin toxicity.
2 citations
,
January 2012 in “Pharmaceutical Methods” In this study, the researchers reported that their proposed methods accurately determined the studied drug with good recovery rates despite the presence of oxidative degradation products.
This research suggests that plucked hair follicles may serve as a reliable surrogate tissue for tumor biopsies in drug development, based on a mouse model linking hair and tumor pharmacodynamic responses.
February 2024 in “Institutional Repository of the Federal Technological University of Paraná (RIUT) (Federal University of Technology – Paraná)” This review examines the molecular effects of photobiomodulation therapy, particularly its influence on gene and protein expression related to inflammation and cell functions, but reports no new clinical results.
August 2024 in “Journal of Biomedical Research & Environmental Sciences” This review consolidates existing research showing that lower SHBG levels are significantly associated with adverse reproductive, metabolic, and cardiovascular outcomes, suggesting its importance as a marker in managing various health conditions.
5 citations
,
October 2019 in “Giornale italiano di dermatologia e venereologia” This review highlights the potential benefits of biotin in treating skin disorders related to biotin deficiency but reports no new clinical results.
48 citations
,
April 2019 in “ACS Applied Materials & Interfaces” In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
2 citations
,
May 2006 in “Archives of Pathology & Laboratory Medicine” This case report describes a 40-year-old woman with Birt-Hogg-Dubé syndrome diagnosed with multiple chromophobe renal cell carcinomas, highlighting the importance of recognizing associated dermatologic lesions for early intervention.
February 2023 in “American Journal of Biomedical and Life Sciences” The researchers reported that hair bio element median derivatives bioassay is an effective and reliable method for evaluating the nutritional status of various bio elements, offering a non-invasive approach for nutritional health surveillance and precision medicine.
31 citations
,
February 1983 in “American Journal of Clinical Nutrition” In this study, two patients with long-term total parenteral nutrition and no biotin intake experienced hair regrowth after biotin supplementation, suggesting biotin deficiency can lead to alopecia.
31 citations
,
August 1975 in “Journal of Pharmaceutical Sciences” This study found that different species metabolized minoxidil into various products, with monkeys and humans showing similar profiles primarily excreting a glucuronide conjugate, while rats and dogs showed distinct differences.
April 2018 in “Radiotherapy and Oncology” Mitochondria may influence how cells respond to radiation, affecting nearby non-irradiated cells.