Biotin: Overview of the Treatment of Diseases of Cutaneous Appendages and Hyperseborrhea

The document from October 1, 2019, reviewed the role of biotin, a vitamin B, in treating common skin disorders associated with biotin deficiency. Biotin deficiency, which can be congenital or acquired due to conditions like inflammatory bowel disorders, a diet rich in avidin, magnesium deficiency, smoking, and certain treatments, can lead to skin disorders. The review found that biotin administration could improve hair loss treatment when a deficiency is detected through patient history, clinical examination, and serum biotin levels. Biotin was also found to be effective in treating seborrheic dermatitis and comedonal acne, especially when used with topical retinoids for acne, as it helps control flaking and irritation. The document emphasized that biotin has excellent tolerability and no risk of hypervitaminosis, even with high doses, but its administration should be controlled by physicians and follow a medical diagnosis and prescription.