Low Level of Maternal Biotin Intake Changes the Expression of Biotin Transporter in Dams and Fetuses in Mice

    December 2014
    Hiromi Sawamura, Yoshie Ishii, Ryoko Shimada, Masahiro Yuasa, Munetaka Negoro, Toshiaki Watanabe
    TLDR Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.
    The study investigated the effects of low maternal biotin intake on the expression of biotin transporters in both dams and fetuses in mice. Biotin, a B-group vitamin, is crucial for several metabolic pathways, and its deficiency can lead to skin disorders, hair loss, and other health issues. Although biotin deficiency is rare due to its presence in various foods, the research highlighted that insufficient biotin intake during pregnancy could alter the expression of biotin transporters, potentially impacting fetal development and health.
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