Influence of FHIT on Benzo[a]pyrene-Induced Tumors and Alopecia in Mice: Chemoprevention by Budesonide and N-Acetylcysteine

    Roumen Balansky, Francesco D’Agostini, G. Ganchev … Silvio De Flora
    Studysummary This study reported that heterozygosity for FHIT affects mice's susceptibility to spontaneous alopecia areata and to certain preneoplastic lesions induced by benzo[a]pyrene, but does not change how they respond to budesonide and N-acetyl-L-cysteine.
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    Research cited in this study 4

    1. Evidence of Hair Loss After Subacute Exposure to 2-Chloroethyl Ethyl Sulfide, a Mustard Analog, and Beneficial Effects of N-Acetylcysteine Journal of Biochemical and Molecular Toxicology · 2004
    2. P53 Involvement in the Control of Murine Hair Follicle Regression American Journal of Pathology · 2001
    3. Genetic Control of Cytokines Dermatologic clinics · 1996
    4. Human Hair Follicle Benzo[a]pyrene and Benzo[a]pyrene 7,8-diol Metabolism: Effect of Exposure to a Coal Tar-Containing Shampoo Journal of Investigative Dermatology · 1987

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