Evidence of Hair Loss After Subacute Exposure to 2-Chloroethyl Ethyl Sulfide, a Mustard Analog, and Beneficial Effects of N-Acetylcysteine

    January 2004 in “ Journal of Biochemical and Molecular Toxicology ”
    Diptendu Chatterjee, Sanjoy Mukherjee, Milton Smith, Salil K. Das
    Image of study
    TLDR Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.
    In 2004, researchers discovered that guinea pigs exposed to 2-chloroethyl ethyl sulfide (CEES), a mustard gas analog, experienced significant hair loss without visible skin damage, indicating that hair loss could be a biomarker for subacute mustard gas exposure. Microscopic examination showed hair follicle regression and decreased keratinocyte proliferation. Pre-treatment with N-acetylcysteine (NAC) was found to prevent this hair loss, suggesting NAC's potential as a treatment for mustard gas toxicity. The exact number of guinea pigs involved in the study was not mentioned.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 1000+ results

      community 2 months minoxidil, vitamins and micro needling

      in Minoxidil  486 upvotes 3 days ago
      The conversation discusses using minoxidil, vitamins, and microneedling for hair loss treatment over two months. Users inquire about the specific vitamins used and the ease of microneedling.

      community 2.5 years 1mg finasteride daily

      in Progress Pictures  4417 upvotes 4 days ago
      Significant hair regrowth was achieved after 2.5 years of taking 1 mg finasteride daily, without using minoxidil or microneedling. Minor side effects included a slightly thinner beard and longer time to finish during sex.

      community 2 Year Finasteride Only Progress (41M)

      in Update  203 upvotes 4 days ago
      A 41-year-old man shared his two-year progress using finasteride for hair regrowth, noting significant improvement but wishing he had started earlier. He plans to add oral minoxidil to his routine despite concerns about potential side effects, emphasizing the importance of starting treatment early to combat hair loss.

      community 2 months progress, so there is hope.

      in Progress Pictures  126 upvotes 5 days ago
      A user shared their 2-month hair regrowth progress using 5% minoxidil, 0.5mg finasteride, and a 1mm dermaroller. They experienced some side effects like reduced morning erections, stomachache, and anxiety.

      community 2 months | 30M | Topical finasteride/minoxidil

      in Progress Pictures  86 upvotes 5 days ago
      A 30-year-old man shares his positive experience with a topical solution containing 0.1% finasteride, 7.5% minoxidil, tretinoin, caffeine, and fluocinolone acetonide after experiencing side effects from oral finasteride and no results from 5% minoxidil. He reports noticeable hair growth in two months with minimal side effects, attributing success to the new topical combination.

    Similar Research

    5 / 1000+ results