Dosimetry for Synchrotron X-Ray Microbeam Radiation Therapy
January 2007
in “
mediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich)
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Studysummary This study analyzed dosimetric quantities in x-ray microbeam radiation therapy and found that the peak-to-valley dose ratio decreases with depth in the irradiated object.
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This study focused on dosimetric analysis for x-ray microbeam radiation therapy, utilizing both calculations and measurements. Monte Carlo simulations were used to analyze dose deposition from single and arrays of microbeams, revealing that the peak-to-valley dose ratio decreased with depth. The air kerma from the high-flux synchrotron x-ray beam was measured using a thimble-type ionization chamber, and the x-ray spectrum was assessed via powder diffraction. Radiochromic film proved effective for quick qualitative dose distribution measurements, while a MOSFET detector was used to measure doses inside and near the microbeam.