Dosimetry for Synchrotron X-Ray Microbeam Radiation Therapy
TLDR Microbeam radiation therapy's dose distribution changes with depth.
This study focused on dosimetric analysis for x-ray microbeam radiation therapy, utilizing both calculations and measurements. Monte Carlo simulations were used to analyze dose deposition from single and arrays of microbeams, revealing that the peak-to-valley dose ratio decreased with depth. The air kerma from the high-flux synchrotron x-ray beam was measured using a thimble-type ionization chamber, and the x-ray spectrum was assessed via powder diffraction. Radiochromic film proved effective for quick qualitative dose distribution measurements, while a MOSFET detector was used to measure doses inside and near the microbeam.