Planar Proton Minibeam Irradiation Elicits Spatially Confined DNA Damage in a Human Epidermis Model

    March 2022 in “ Cancers ”
    Harry Scherthan, Stephanie-Quinta Wagner, Jan Grundhöfer … Judith Reindl
    Studysummary This study found that proton minibeam radiotherapy demonstrated a potential tissue-sparing effect in epidermis models by spatially confining DNA damage, suggesting reduced side effects in radiotherapy.
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    Research cited in this study 3

    1. PMB Flash - Status And Perspectives Of Combining Proton Minibeam With Flash Radiotherapy Journal of Cancer Immunology · 2019
    2. Skin Toxicity of Anti-Cancer Therapy Journal der Deutschen Dermatologischen Gesellschaft · 2008
    3. The Use of Elongate Microbeams of X-Rays for Simulating the Effects of Cosmic Rays on Tissues: A Study of Wound Healing and Hair Follicle Regeneration Radiation Research · 1963