Optimization of X-Ray Microplanar Beam Radiation Therapy for Deep-Seated Tumors by a Simulation Study

The study utilized a Monte Carlo simulation to investigate the energy dependence on the transverse dose distribution in microplanar beam radiation therapy (MRT) for deep-seated tumors. It was found that increasing the energy of X-rays reduced the area of the valley region, which is crucial for the recovery of normal tissue. The study concluded that the optimal X-ray energy for MRT was between 100–300 keV, depending on the effective peak dose to the target tumors and the tolerable surface dose. The research also proposed parameters for further optimization of MRT for deep-seated tumors.