Bubble-Based Drug Delivery Systems: Next-Generation Diagnosis to Therapy

The document reviews the potential of microbubbles (MBs) and nanobubbles (NBs) in drug delivery systems, emphasizing their advantages in targeted therapy and imaging. MBs are effective as ultrasound contrast agents but face challenges in tissue penetration, while NBs, due to their smaller size, can deliver drugs and genes to targeted tissues, enhancing cancer treatments and minimizing side effects. NBs are also explored for gene delivery in cardiovascular and central nervous system disorders. The use of ultrasound to trigger drug release from NBs improves precision and efficiency. Despite challenges like stability and bubble design optimization, bubble-based systems show promise for personalized therapy and diagnosis, with ongoing clinical trials highlighting their potential in treating conditions like cancer, osteoporosis, and acute medical conditions.