30 citations
,
November 2019 in “Genetics selection evolution” This study found that in Chinese goat breeds, specific genetic variations, particularly in Tibetan Cashmere goats, are associated with traits like hair growth and adaptation to high-altitude environments.
26 citations
,
September 2024 in “Perspectives in Clinical Research” This article discusses drug repurposing as a strategy to find new uses for existing medications, highlighting its potential benefits like faster development and lower costs, while also addressing challenges such as drug specificity, ethical concerns, and regulatory issues.
26 citations
,
December 2020 in “International Journal of Molecular Sciences” This review explores current and emerging treatments for polycystic ovary syndrome, focusing on managing hyperandrogenism and cardiometabolic risk, but reports no new clinical results.
26 citations
,
September 2014 in “Neuroscience Letters” This study found that metformin did not prevent gentamicin-induced hearing loss and even worsened auditory threshold shifts and caused adverse effects at higher doses in guinea pigs.
26 citations
,
August 2008 in “Clinical endocrinology” This paper summarizes proceedings from a PCOS Special Interest Group, reporting recent advances in the understanding of PCOS follicular abnormalities, associated cardiovascular risks, and dermatological issues, but does not present new clinical findings.
25 citations
,
February 2024 in “Pharmaceutics” This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.
21 citations
,
February 2023 in “Pharmaceuticals” This study reports that extracts from pomegranate leaves contain bioactive compounds with antioxidant, antimicrobial, and skin-beneficial properties, suggesting their potential use in nutraceutical and cosmeceutical applications.
16 citations
,
December 2021 in “Frontiers in Endocrinology” This review discusses the role of sex hormones in COVID-19 severity and reports no new clinical results; the authors suggest further research for gender-based personalized treatment options.
14 citations
,
November 2024 in “Pharmaceuticals” This study found that using spanlastics, a nano, surfactant-based drug delivery system, improved the bioavailability, drug release characteristics, and pharmacokinetic behavior of famotidine, a poorly soluble drug, by enhancing its dissolution and membrane permeation.
14 citations
,
February 2023 in “Frontiers in Bioengineering and Biotechnology” This review details various components used in hydrogel composites for treating chronic diabetic ulcers and highlights potential future materials but reports no new empirical findings.
14 citations
,
August 2021 in “Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy” This research discusses the potential antitumor effects of metformin, a common diabetes medication, noting its controversial influence on different malignant tumors and its uncertain mechanisms. Understanding these effects on tumors may aid in the development of new cancer treatments.
13 citations
,
December 2012 in “Medical mycology case reports” In this case report, an atypical form of tinea favosa in an 11-year-old girl was initially misdiagnosed, highlighting the importance of mycological examination for accurate diagnosis, especially when diffuse scalp scaling is present.
12 citations
,
October 2023 in “Journal of Mind and Medical Sciences” This source presents a comprehensive review of the literature on diabetes, highlighting the complex factors involved in its development and the importance of prevention, early diagnosis, and a multi-faceted treatment approach for effective management.
12 citations
,
June 2023 in “International Journal of Molecular Sciences” This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
11 citations
,
March 2023 in “Life” This study found that the aerial parts (leaves and flowers) of Scorzonera undulata from southwest Tunisia demonstrated higher antioxidant activity and beneficial biological properties compared to its tubers.
11 citations
,
July 2019 in “International journal of women’s dermatology” This review discusses the links between sex hormones, metabolic syndrome, and skin conditions, and reports no new clinical results; the authors recommend monitoring patients with specific skin conditions for metabolic complications.
10 citations
,
May 2025 in “Nutrition & Metabolism” This review highlights that metabolic syndrome is intricately linked with various skin conditions such as inflammatory skin diseases and tumors through mechanisms involving insulin resistance and chronic inflammation, aiming to guide clinicians on effective treatments and preventive strategies for affected patients.
10 citations
,
March 2024 in “Frontiers in Bioengineering and Biotechnology” This review examined photothermal hydrogels, biomedically innovative materials responsive to near-infrared stimulation, which hold promise for enhancing infection control and tissue regeneration. The authors highlighted their unique properties, construction methods, and potential applications while also discussing existing challenges and future research directions.
10 citations
,
June 2022 in “Development” This study suggests that distinct chromatin topologies allow different lineage-specific enhancers to regulate Hoxd genes in mouse vibrissae and chicken feather primordia, while conserved regulatory elements maintain transcriptional robustness in the embryonic trunk across species.
9 citations
,
December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
9 citations
,
December 2022 in “Phytomedicine” This review discusses the pharmacology, toxicology, and clinical efficacy of flavonoids and saponins, highlighting the need for more data on their pharmacokinetics, interactions, and toxicities as most research is still in vitro.
8 citations
,
October 2022 in “International Journal of Molecular Sciences” This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.
7 citations
,
August 2025 in “European Journal of Endocrinology” The authors concluded that incorporating routine endocrinology consultations into transplant care could address CNI-related endocrine toxicities, but prospective studies are needed to assess the impact on graft and patient survival.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.
6 citations
,
August 2024 in “Aesthetic Plastic Surgery” This study analyzed RSN complications in 18 hair transplantation patients and found that smoking, diabetes, and hypertension may increase risk, highlighting the need for prevention strategies and timely treatment.
6 citations
,
March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
6 citations
,
February 2023 in “Biomaterials Research” This review explores the different types of hydrogels used to repair diabetic ulcers, the mechanisms involved, and the limitations in developing these technologies for clinical use, but it reports no new clinical results.
6 citations
,
September 2020 in “African Journal of Urology” This study found that prostate size varies significantly among different ethnic groups in South-Kivu, with the Lega having larger prostate volumes compared to other groups.
5 citations
,
May 2024 in “Developmental Cell” Lower GATA3 levels in mice help hair regrow by changing certain immune cells.
5 citations
,
October 2022 in “Heliyon” This review discusses infertility in polycystic ovary syndrome and therapeutic options, without reporting new results; it underscores the importance of personalized treatment plans based on patient needs and disease characteristics.