Photothermal Hydrogels for Infection Control and Tissue Regeneration

    Siyu Sun, Guangyang Jiang, Jianru Dong, Xi Xie, Jinfeng Liao, Yongqiang Tian
    Studysummary This review examined photothermal hydrogels, biomedically innovative materials responsive to near-infrared stimulation, which hold promise for enhancing infection control and tissue regeneration. The authors highlighted their unique properties, construction methods, and potential applications while also discussing existing challenges and future research directions. Our plain-language summary of this paper — not a Tressless recommendation.
    Photothermal hydrogels are promising materials for infection control and tissue regeneration due to their ability to convert light into heat, which can kill bacteria and promote tissue healing. These hydrogels incorporate photothermal agents (PTAs) that enhance antibacterial activity and support tissue repair by modulating local temperatures. They can be prepared through various methods, such as integrating PTAs into hydrogels or forming photothermal nanoparticles within them. Despite their potential, challenges like PTA aggregation and potential toxicity remain. Future research should focus on improving stability, photothermal efficiency, and biocompatibility to advance clinical applications.
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