Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control

    July 2025 in “ Gels ”
    German Jiménez-Gastélum, Carlos Esteban Villegas‐Mercado, Juan Luis Cota-Quintero … Mercedes Bermúdez
    Studysummary This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.
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    Research cited in this study 5

    1. Biomaterial-Based Mechanical Regulation Facilitates Scarless Wound Healing With Functional Skin Appendage Regeneration Military Medical Research · 2024
    2. In Vitro and In Vivo Evaluation of Chitosan/HPMC/Insulin Hydrogel for Wound Healing Applications Bioengineering · 2024
    3. Wound Microbiota and Its Impact on Wound Healing International journal of molecular sciences · 2023
    4. Cellular and Molecular Mechanisms of Repair in Acute and Chronic Wound Healing British Journal of Dermatology · 2015
    5. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression Journal of Investigative Dermatology · 2009