Wound Microbiota and Its Impact on Wound Healing

December 2023 in “ International journal of molecular sciences ”

M. Zielińska, Agnieszka Pawłowska, Anna Orzeł, Luiza Sulej, Katarzyna Muzyka-Placzyńska, A. Baran, Dagmara Filipecka‐Tyczka, Paulina Pawłowska, Aleksandra Nowińska, Joanna Bogusławska, Anna Kajdy

wound microbiota commensal bacteria Staphylococcus epidermidis pathogenic bacteria Staphylococcus aureus probiotics tissue regeneration immune responses chronic inflammation microbiota-based wound care

TLDR Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.

The review "Wound Microbiota and Its Impact on Wound Healing" highlights the significant role of wound microbiota in the healing process, emphasizing that commensal bacteria can both promote and hinder healing. Beneficial bacteria like Staphylococcus epidermidis aid healing by modulating immune responses and promoting tissue regeneration, while pathogenic bacteria like Staphylococcus aureus can cause infections and chronic inflammation, delaying healing. The review explores microbiota-based wound care, including probiotics and specific bacteria to enhance tissue repair, but notes that further research is needed to determine the ideal microbiota composition and understand the precise mechanisms of microbiota influence.

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